Lymphomatoid papulosis (LyP) is a chronic recurrent dermatosis characterized by involuting and recurring papules, plaques, and nodules showing histolotic features suggesting malignant lymphoma. On histologic grounds, it is divided into two types
:
type
A and type B. In type A, large atypical lymphocytes are the main cellular component and most of thes4e express CD-30(Ki-1) antigen, which has been previously thought to be specific for Reed-Sternberg cells of Hodgkin's disease. In type B,
cerebriform
mononuclear lymphocytes similar to those in mycosis fungoides predominates.
We report two cases of lymphomatoid papulosis, type A and type B, respectively. The large atypical cells in type A LyP expressed Ki-1 antigen. Both cases were treated with PUVA and the outcome of the treatment has been fair.(Kor J Dermatol 1995 ;
33(1)
: 160~165)
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